Silk Shield
Gentle, research-informed topical support for the next stage of a professional skincare routine.
- BPC-157 + Acemannan — a 15-amino-acid research peptide with an Aloe vera-derived bioactive polysaccharide in one topical formula.
- Post-procedure positioning — developed for topical use following appropriate professional cosmetic or aesthetic procedures, as directed by your provider.
- Gentle application — developed for skin that may temporarily feel sensitive, tight or dry following a professional procedure.
- Targeted topical format — apply a thin, even layer directly to the intended external area.
- Professional aftercare support — intended to complement, not replace, a provider-directed post-procedure routine.
- Quality-focused formula — fragrance-free and cruelty-free.
Recovers faster. Recovers better.*
Formulated for the critical recovery window after surgery, microneedling, dermabrasion and other skin interventions — gentle enough for compromised, post-procedure skin without sacrificing potency.The actives, quantified
- 15-amino-acid research peptide
BPC-157
4 mg per 3 oz (85 g) container
Works at the cellular level to accelerate tissue repair* — and stays active in a neutral cream base, with no carrier or penetration enhancer required.
- Sequence GEPPPGKPADDAGLV
- Class Pentadecapeptide, 1,419 Da
- Aloe vera inner-leaf polysaccharide
Acemannan
3 g per 3 oz (85 g) container
Read by the innate immune system's pattern-recognition receptors — the mannose receptor, TLR-4 and TLR-5 — and studied for cellular communication and repair.
- Backbone β-(1,4)-linked acetylated polymannose
- Average mass 40–60 kDa
Full ingredients: Purified Water, Aloe Vera Leaf Juice, Emulsifying Wax, Cetyl Alcohol, Stearic Acid, Glycerin, Phenoxyethanol, Caprylyl Glycol, BPC-157. Fragrance-free. Acemannan is the principal bioactive polysaccharide fraction of the Aloe vera inner leaf — the Aloe Vera Leaf Juice on this list is its source.
Two pathways, one convergence
The combination's rationale, in the dossier's own words: one ingredient raises the VEGF signal, the other the sensitivity of its receiver. Ligand and receptor, approached from different directions, converging on fibroblast proliferation, type I collagen and balanced angiogenesis.
The full mechanism
BPC-157 is a synthetic 15-amino-acid peptide — a partial sequence of Body Protection Compound, a protein isolated from human gastric juice. The published literature reports a defined cascade: VEGFR2 receptor activation, then Src/FAK and Akt, then eNOS and nitric-oxide bioavailability — alongside a fibroblast branch (FAK–paxillin signaling, F-actin formation) and an early transcriptional burst, with egr-1 expressed by 15 minutes and its own repressor nab2 arriving almost immediately after. The reviewing group proposes that self-limiting loop as the reason repair is rapid but not fibrotic.
The peptide's signature is balance, not one-way stimulation: in rat models it counteracts a blocked NO system (L-NAME) and an over-stimulated one (L-arginine) alike, with free-radical formation falling alongside — and angiogenesis is promoted in tendon, ligament and muscle models while opposed in the cornea, where transparency depends on keeping vessels out.
Acemannan approaches repair from the other direction. An acetylated polymannose from the inner gel of Aloe vera, it is recognized by pattern-recognition receptors of the innate immune system — the mannose receptor, TLR-4 and TLR-5 — and in gingival-fibroblast studies it raised proliferation and upregulated KGF-1, VEGF and type I collagen.
Convergent nodes across separate literatures
- Fibroblast proliferation
- Type I collagen
- VEGF / angiogenesis
How to use
- Follow your provider's instructionsUse it only when that use is consistent with the aftercare instructions given for your specific procedure.
- Begin with clean handsWash and dry your hands before touching the area or the pump dispenser.
- Confirm the skin is intactThe label directs that the product is not applied to broken or irritated skin. Your provider decides when application is appropriate.
- Cleanse as directedPrepare the skin according to the instructions from the professional guiding your aftercare.
- Apply a small amountDispense a small amount and apply a thin, even layer to the intended external area, massaging until absorbed.
- Use only as directedKeep to the frequency stated on the product label or given by your professional. Skin after a recent procedure should not be rubbed or exfoliated.
Label directions: “Apply a small amount to the desired area and massage until absorbed. For external use only.”
Where it belongs
Provider-directed procedures
- Microneedling
- Cosmetic laser procedures
- Dermabrasion / microdermabrasion
- Chemical exfoliation
- Cosmetic injections
- Professional facial procedures
Provider guidance determines use — it is not suitable for every procedure or for immediate use after every one. Always follow the instructions given by your provider.
Intended application areas
- Face
- Neck
- Décolletage
- Hands
- Localized areasProvider-guided
Held to a standard
- Fragrance-free
- Cruelty-free
- For external use only
- Provider-directed use
- Controlled pump dispensing
- For adults
Cautions and storage
Usage cautions
- For external use only. Avoid contact with eyes; do not apply inside the mouth.
- Do not apply to broken or irritated skin.
- If irritation occurs, discontinue use.
- Consult the provider guiding your aftercare before combining with retinoids, acids, exfoliants or other active products.
- Keep out of reach of children.
- Consult a healthcare professional before use if pregnant or nursing.
Storage
About Silk Shield
Ingredients, directions and specifications for this exact product.
Silk Shield is a specialized topical formula developed for use within professional cosmetic and aesthetic aftercare routines. It combines BPC-157, a 15-amino-acid research peptide, with Acemannan, a bioactive polysaccharide derived from Aloe vera.
The formula is designed to provide gentle, targeted topical support for skin that may temporarily feel dry, sensitive or tight following a professional procedure. It is intended for application to intact external skin, at a point in the aftercare routine determined by your provider.
Silk Shield reflects American Sciences' focus on pairing research-informed biotechnology with carefully selected bioactive compounds in a convenient topical format. It is a supportive topical cosmetic product, and it is not a drug.
The research described in American Sciences' product materials concerns the individual ingredients and is not clinical evidence for the finished product. Topical human efficacy has not been clinically established.
Ingredients
How to use
Product facts
| Product type | Face recovery cream, for use within a professional post-procedure aftercare routine |
|---|---|
| Net contents | 3 oz (85 g) in a pump container designed for controlled, hygienic dispensing |
| Key actives | BPC-157, 4 mg per container, and proprietary Acemannan extract, 3 g per container |
| Intended use | External topical application to intact skin following professional cosmetic or aesthetic procedures, subject to your provider's guidance |
| Application area | Face and other external areas, as directed by your provider. Not for use in the eyes or mouth. |
| Delivery format | A targeted topical cream intended to place the formulation directly onto a specific external area rather than provide systemic delivery |
| Sensory profile | Fragrance-free |
| Recommended user | Adults seeking a gentle topical product to complement a professional post-procedure skincare routine |
| Storage | Store in a cool, dry place away from direct sunlight |
| Distributed by | American Sciences LLC, 8 The Green STE B, Dover, DE 19901 |
Where does Silk Shield fit in a post-procedure routine?
Which procedures is it made for?
Where can I apply it?
What is BPC-157?
What is Acemannan?
Is it fragrance-free?
What should I know before using it?
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Note on statements marked with an asterisk: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Research described on this page reflects published studies of the individual ingredients.